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The neurotrophic components GDNF and BDNF Participate in an essential purpose in neuroprotection. Selective serotonin-reuptake inhibitors (SSRI), at present utilised as anti-depressants, are noted to possess a constructive effect on neurotrophic element expression. In a transgenic MSA mouse model fluoxetine has long been shown to boost GDNF and BDN

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